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Allergy Myth Busters: Is All Immunotherapy the Same?

December 20, 2022 by

Allergy Myth Busters: Is All Immunotherapy the Same?

by Allergy Partners
December 20, 2022

Allergenic Extract

Inspired by one of our favorite television shows, Allergy Myth Busters looks at a number of popularly held beliefs about allergy. But are these myths just urban legends or are they true?

MYTH: All immunotherapy is the same

THE BACKGROUND: Immunotherapy (also known as allergy shots) is an effective treatment for allergic nasal and eye symptoms (allergic rhinitis and allergic conjunctivitis), allergic asthma, and eczema. Immunotherapy can also be used to treat stinging insect allergies. Small amounts of the allergen (the substance that patients are allergic to) are injected in regular intervals over several years to desensitize patients to those substances. Immunotherapy is designed to alleviate current symptoms as well as prevent the progression of allergic disease. Relief of symptoms also continues after allergy shots are stopped making it a cost effective and beneficial treatment for many allergy sufferers. Several people and even physicians believe that all immunotherapy is the same.

THE SCIENCE: Not all allergen immunotherapy is created equally.

Allergy testing identifies specific allergies in each patient. Small amounts of these allergens are then combined to make allergy shots. Immunotherapy is tailored specifically for each patient based on their degree of allergies and underlying disease. Current medications and other coexisting diseases should also be taken into account when formulating the strength of these extracts. If the dose of allergen included in the allergy shots is too weak, the patient will not mount an effective or long lasting immune response. If the dose of allergen in the allergy shots is too strong, the patient will have increased risk of an allergic reaction or adverse reaction to the shots.

Board certified allergists are specialists who have performed the highest level of education based on national standards for the field of allergy and immunology. They are extensively trained on doses and concentrations of allergens that are the most effective and safe. They are also trained on specific allergens that are more prominent in their local area and are aware of any cross reactivity between allergens that might affect your treatment response. Here at Allergy Partners, our providers have many years of experience in formulating allergen immunotherapy, and our immunotherapy program is the nation’s largest. Our physicians continuously review studies and safety data to determine the most up to date recommendations on the safest and most effective allergen dosing for allergy shots.

THE VERDICT: The Myth that all allergen immunotherapy is the same has been busted.

Ingrid Hoffmann, MD
Allergy Partners of the Piedmont

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Filed Under: Allergy Shots

Allergy Partners Announces Collaboration With Aimmune Therapeutics

November 29, 2022 by

Allergy Partners Announces Collaboration With Aimmune Therapeutics

by Allergy Partners
November 29, 2022

Allergy Partners

Allergy Partners Announces Collaboration With Aimmune Therapeutics to Provide Palforzia® [Peanut (Arachis Hypogaea) Allergen Powder-DNFP] Directly to Patients

Collaboration strengthens patient access to PALFORZIA through Allergy Partners’ national network of specialty practices

Children and teenagers aged 4 through 17 years with a confirmed diagnosis of peanut allergy to benefit from direct access to high-quality treatment and improved specialty care

Important step forward for Allergy Partners, less than one year after its strategic partnership with B-Flexion, the long-term investor in the allergy sector

ASHEVILLE, N.C. & BRISBANE, Calif.–(BUSINESS WIRE)–Allergy Partners, the nation’s largest single specialty allergy practice group leading the development and delivery of high-quality health care for patients with asthma and allergic disease, today announced a strategic collaboration with Aimmune Therapeutics, Inc., a Nestlé Health Science company developing pharmaceutical therapies to prevent, manage, and treat food, gastrointestinal, and metabolic-related diseases, to provide Allergy Partners’ patients aged 4 through 17 years with a confirmed diagnosis of peanut allergy with direct access to PALFORZIA, the first and only FDA-approved peanut allergy treatment.

PALFORZIA was approved in January 2020 by the U.S. Food and Drug Administration (FDA) as an oral immunotherapy (OIT) for the mitigation of allergic reactions, including anaphylaxis, that may occur with accidental exposure to peanut in patients aged 4 through 17 years with a confirmed diagnosis of peanut allergy. It is not indicated for the emergency treatment of allergic reactions, including anaphylaxis. PALFORZIA is to be used in conjunction with a peanut-avoidant diet.

Allergy Partners’ nation-wide care network provides high-quality health care for patients with asthma and allergic diseases, promoting education, research, and innovation in the field. As a result of this collaboration, Allergy Partners will begin to provide PALFORZIA directly to patients through its specialty pharmacy, Allergy Partners Therapeutics (APT), across its entire national network of 64 practices and 126 community locations in 19 states.

“Supported by the recent strategic investment from B-Flexion, our commitment will continue to be to provide the best possible care to our patients and improve health outcomes across an expanding allergy network, and this unique collaboration with Aimmune will enable us to improve patient access to this important treatment through APT and our network of dedicated providers,” said Dr. Bill McCann, Chief Medical Officer of Allergy Partners. “We are pleased to be working with Aimmune, which is at the forefront of developing allergy therapies like PALFORZIA that have the potential to help transform the lives of patients that often have few or no treatment options available to them.”

“PALFORZIA is an important treatment option for patients living with peanut allergy, helping to reduce the risk of severe allergic reactions due to accidental exposure, and enabling them to live with fewer restrictions,” said Andrew Oxtoby, President and CEO, Aimmune Therapeutics. “Aimmune is committed to help ensure that all eligible patients who wish to access PALFORZIA are able to do so, and the announcement today of our collaboration with Allergy Partners marks another step toward that goal.”

Please see the below Important Safety Information or visit www.PALFORZIA.com for the full Prescribing Information, including Boxed WARNING and Medication Guide.

What Is PALFORZIA?

PALFORZIA is a treatment for people who are allergic to peanuts. PALFORZIA can help reduce the severity of allergic reactions, including anaphylaxis, that may occur with accidental exposure to peanut. PALFORZIA may be started in patients aged 4 through 17 years old. If you turn 18 years of age while on PALFORZIA treatment you should continue taking PALFORZIA unless otherwise instructed by your doctor.

PALFORZIA does NOT treat allergic reactions and should not be given during an allergic reaction.

You must maintain a strict peanut-free diet while taking PALFORZIA.

Important Safety Information

PALFORZIA can cause anaphylaxis which may be life-threatening. You will receive your first dose in a healthcare setting under the observation of trained healthcare staff.

You will receive the first dose of all dose increases in a healthcare setting.

In the healthcare setting, you will be observed for at least 1 hour for signs and symptoms of a severe allergic reaction.

If you have a severe reaction during treatment, you will need to receive an injection of epinephrine immediately and get emergency medical help right away.

You will return to the healthcare setting for any trouble tolerating your home doses.

Stop taking PALFORZIA and get emergency medical treatment right away if you have any of the following symptoms after taking PALFORZIA:

  • Trouble breathing or wheezing
  • Chest discomfort or tightness
  • Throat tightness
  • Trouble swallowing or speaking
  • Swelling of your face, lips, eyes, or tongue
  • Dizziness or fainting
  • Severe stomach cramps or pain, vomiting, or diarrhea
  • Hives (itchy, raised bumps on skin)
  • Severe flushing of the skin

Because of the risk of severe allergic reactions, PALFORZIA is only available through a restricted program called the PALFORZIA Risk Evaluation and Mitigation Strategy (REMS) Program. Talk to your healthcare provider for more information about the PALFORZIA REMS program and how to enroll.

You should NOT take PALFORZIA if you have uncontrolled asthma, or if you ever had eosinophilic esophagitis (EoE) or other eosinophilic gastrointestinal disease.

Tell your doctor if you are not feeling well prior to starting treatment with PALFORZIA. Your doctor may decide to delay treatment until you are feeling better. Also tell your doctor about any medical conditions you have and if you are taking or have recently taken any other medicines, including medicines obtained without a prescription and herbal supplements.

Your doctor may decide that PALFORZIA is not the best treatment if:

  • You are unwilling or unable to receive (or self-administer) injectable epinephrine.
  • You have a condition or are taking a medication that reduces the ability to survive a severe allergic reaction.

What are the possible side effects of PALFORZIA?

The most commonly reported side effects of PALFORZIA were: stomach pain, vomiting, feeling sick, itching or burning in the mouth, throat irritation, cough, runny nose, sneezing, throat tightness, wheezing, shortness of breath, itchy skin, hives, and/or itchy ears.

PALFORZIA can cause anaphylaxis which may be life-threatening. PALFORZIA can cause stomach or gut symptoms including inflammation of the esophagus (called eosinophilic esophagitis). Symptoms of eosinophilic esophagitis can include:

  • Trouble swallowing
  • Food stuck in throat
  • Burning in chest, mouth, or throat
  • Vomiting
  • Regurgitation of undigested food
  • Feeling sick

For additional information on the possible side effects of PALFORZIA, talk with your doctor or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

About Allergy Partners

Allergy Partners, PLLC which in December 2021 received a strategic investment from B-Flexion, the private investment firm managing funds on behalf of the Bertarelli Family, is the largest single specialty practice group, and recognized as leaders in the development and delivery of high-quality health care for patients with asthma & allergic disease. Our vast care network of providers works together to promote education, research & innovation in the field of allergy & asthma care. Learn more about www.allergypartners.com

About Aimmune Therapeutics

Aimmune Therapeutics, part of Nestlé Health Science, is a biopharmaceutical company that aspires to be a global leader in developing innovative medicines to prevent, manage, and treat food, gastrointestinal (GI), and metabolic-related diseases for those with few or no treatment options. Aimmune was built on the belief that families deserve standardized, regulatory-approved, science-driven treatments that reduce their daily burden and help them better manage these conditions.

For more information about Aimmune, please visit www.aimmune.com

Contacts

Blair Hennessy, Abernathy MacGregor
(212) 371-5999 / bth@abmac.com

Georgina Vincent, Head of External Communications
(747) 758-9524 / gvincent@aimmune.com

https://www.businesswire.com/news/home/20221013006052/en/

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Filed Under: News

Back-to-School: Basics for Kids with Allergies

August 15, 2022 by

Back-to-School: Basics for Kids with Allergies

by Allergy Partners
August 15, 2022

Young Girl Smiling at Doctor

The following guide offers strategies for managing your child’s allergies during the school year.

Managing a child’s allergies is challenging enough when they’re at home – how can you make sure they’re protected during the school day?

Whether your child has food allergies, insect sting allergies, asthma, or another allergy that requires vigilant management, it’s critically important that you use every resource available to you. Here’s how you can ensure your child has a safe and welcoming school year.

Recognize Allergy Signs

Schedule an appointment with your allergist or pediatrician if your child experiences the following symptoms:

  • Frequent respiratory symptoms (itchy eyes, runny nose, sneezing , coughing, wheezing, shortness of breath)
  • Frequent infections (ear, sinus, bronchitis, pneumonia) Changes in skin texture or appearance (rashes, dry patches, hives)

During your visit, the physician will conduct a physical examination and evaluate your child’s symptoms. You will be asked about your child’s dietary habits, environment, and medical history. Your physician will recommend allergy testing or not based on the information provided. If allergy testing is recommended, request a referral to a board-certified allergist.

Your allergist will provide you with instructions to help you prepare for testing. These instructions are designed to maximize the accuracy of the testing and might include the following guidance:

  • Don’t administer antihistamines the week before the test.
  • Avoid any substances that trigger physical symptoms before the test.

Allergy testing might involve the following:

  • Skin Prick Test: Skin prick testing involves introducing a small sample of allergen proteins to the child’s skin and then gently pricking or scratching the skin’s surface. If the child is allergic to a particular substance, inflammation or redness may develop.
  • Blood Test: During immunoglobulin E (IgE) sensitization testing, a blood sample is taken and then analyzed to identify specific antibodies related to different allergens. This type of test is preferred for children who cannot undergo skin prick testing.

The test results will identify any allergens that cause the reaction. Your allergist will explain the test results to you and help you develop an appropriate management plan and emergency action plan.

Create a Management Plan With Your Child’s Allergist

It’s critically important to create a comprehensive allergy management plan if your child is experiencing symptoms that are either disruptive to normal functioning or potentially life-threatening. While management plans must be specific to the child and the type of allergy, they will include the following strategies:

  • Procedures for avoiding allergens.
  • Managing symptoms through medications, diet, or other therapies.
  • Scheduling periodic follow-ups with allergy specialists to monitor the symptoms and adjust medications/therapies as needed.
  • Design an emergency action plan for addressing dangerous allergic responses, including the proper use of epinephrine injectors (EpiPens).

Communicate With Your Child’s Teachers and Appropriate School Staff

Clear communication and collaboration are critical to ensuring your child’s safety and comfort during the school year.

  • Alert your school and school district to your child’s condition: While school districts throughout the United States have different administrative processes, they will generally allow you to access or fill out the necessary documents online. However, whether they require you to visit the enrolment offices or submit the paperwork electronically, always keep digital or physical copies of any paperwork you submit for your own records.
  • Have a meeting with school staff: Communicating your child’s needs with teachers, administrators, and school nurses is essential to creating and maintaining a safe and inclusive school environment. If possible, meet with all staff members who will come in contact with your child, including counselors, homeroom teachers, school mental health aides, and security personnel.
  • Share your allergy action plan with school staff: Collaborating with the child’s healthcare provider, parents can develop an allergy action plan that provides specific steps to be taken during an allergic reaction. This plan should include information about recognizing signs, administering emergency medication, and contacting emergency services if necessary. Sharing this plan with the school staff ensures everyone is prepared to respond appropriately. Moreover, clarify how epinephrine injectors can be easily accessed in case of an allergic reaction or where emergency medication should be stored. It is crucial to establish clear protocols for medication storage and accessibility.
  • Ask to review training records for epinephrine injectors and other interventions: Make sure that every adult that comes in contact with your child can recognize the onset of an allergic response and can intervene appropriately and quickly.

Different Types of Allergies Will Require Different Strategies and Accommodations

Anaphylaxis

Anaphylaxis is an extreme and potentially fatal allergic response. It develops due to an overreaction of the immune system to a substance it perceives as harmful. The most common substances that trigger anaphylaxis are insect venom, certain foods (like peanuts, tree nuts, sesame seed, seafood, milk, and eggs), latex, and medications.

The symptoms of anaphylaxis can occur suddenly and can involve numerous organ systems. The condition is considered a medical emergency requiring immediate intervention. When untreated, anaphylaxis can be life-threatening..

Schools can reduce the risk of anaphylaxis in the following ways:

  • Maintain strict protocols surrounding access to emergency medications like epinephrine injectors.
  • Provide staff-wide training in emergency treatment administration.
  • Provide student training in emergency treatment administration.
  • Provide staff-wide training in recognizing anaphylaxis symptoms.
  • Provide student training in recognizing anaphylaxis symptoms.
  • Make epinephrine injectors easily accessible.
  • Allow students to carry their own prescribed epinephrine injectors.

Food Allergies

Food allergies are becoming increasingly common among children; nearly 6% of children experience food allergies, according to the Centers for Disease Control and Prevention.

A food allergy is a type of immune system response triggered by particular foods. When someone has a food allergy, their immune system misidentifies certain proteins in the food as dangerous and overreacts to them.

Common food allergy symptoms include abdominal discomfort, diarrhea, nausea, vomiting, hives, itching, swollen lips, swollen tongue, and swollen throat. In more serious instances, food allergies can cause anaphylaxis, a potentially deadly reaction.

Schools can accommodate children with food allergies in the following ways:

  • Institute allergy-aware policies in the classrooms.
  • Establish a safe cafeteria environment.
  • Inspect food item ingredient lists regularly.
  • Maintain open communication with parents and guardians.
  • Address allergy or food-related bullying immediately.

Stinging Insect Allergies

Hymenoptera venom allergies, commonly known as insect sting allergies, are allergic reactions that occur in response to the venom injected by stinging insects such as honey bees, yellow jackets, hornets, wasp, and fire ants. These allergies can range from mild, localized reactions to severe systemic reactions, including anaphylaxis.

Schools can accommodate children with insect sting allergies in the following ways:

  • Limit exposure to stinging insects by controlling pests in the common outdoor areas.
  • Provide insect-repellant products.
  • Maintain an allergy-aware classroom by limiting flowers and plants that could attract insects.

Asthma

Asthma is a common, chronic respiratory condition that affects millions of people worldwide, both children and adults. The symptoms of asthma can vary from person to person but typically include wheezing, inability to breathe, coughing, and chest tightness.

Asthma and allergies can be interrelated; asthma can be triggered by certain allergens like dust, pet dander, and pollen.

Schools can accommodate children with asthma in the following ways:

  • Offer asthma education and awareness for students and staff.
  • Screen for asthma triggers and maintain a healthy, clean environment.
  • Provide physical education tailored to the needs of students with asthma.

Latex Allergies

Latex allergies are immune system overreactions to natural rubber latex. Latex allergy symptoms can range from minor to life-threatening. They might include skin eruptions (hives, rashes), respiratory symptoms (sneezing, coughing, a runny nose, shortness of breath), or anaphylaxis.

People with severe latex allergies can be put at risk in an environment where latex particulates are in the air.

Latex allergies sometimes correspond with certain food allergies because they share similar protein structures. Foods that frequently trigger allergic responses in people with latex allergies include avocados, bananas, chestnuts, kiwi, potatoes, and tomatoes.

Schools can accommodate children with latex allergies in the following ways:

  • Make sure school supplies, toys, and furnishings are latex-free.
  • Educate administrators, school nurses, and lunchroom staff about products containing latex and alternative, safe materials.

Allergic Rhinitis (Hay Fever)

Allergic rhinitis, known commonly as hay fever, is a common condition that affects nearly 20% of children in the United States. People affected by hay fever experience a disordered immune response when they inhale allergens (dust, pollen, dust mites, mold) through the mouth or nose. Hay fever symptoms include coughing, sneezing, nasal congestion, fatigue, and watery eyes.

Unmanaged hay fever symptoms can significantly affect a student’s ability to succeed in school. Schools can accommodate children affected by hay fever in the following ways:

  • Limit the presence of allergens (pollen, mold, dust, dander) in the classroom and other common areas.
  • Provide the appropriate resources and supplies (tissues, hand wipes) to maximize comfort for students struggling with hay fever symptoms.
  • Modify outdoor physical education and recess activities to minimize exposure to pollen and other allergens.

Discuss Allergy Management With Your Child

Managing significant allergies can be challenging for a child. It’s important to involve your child in the allergy management strategy early so the processes become second nature.

Choose a relaxed and comfortable environment to start a discussion about your allergy management plan. Make sure it is a safe and open space for your child to ask questions and express their concerns. Encourage them to talk about any fears they may have regarding their allergies, and allow them to be as proactive about their allergy management as their age and abilities allow. Reassure them that you are there to support and help them navigate their allergy management effectively.

Allergy Partners Can Help With Your Child’s Allergies

If you have any questions about allergy management or if you would like to schedule an examination with a board-certified allergist, please contact our helpful representatives today.

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Filed Under: Resources

Black History Month 2021 with Dr. Aerik Williams | Podcast

February 1, 2022 by

Black History Month 2021 with Dr. Aerik Williams | Podcast

by Allergy Partners
February 1, 2022

Aerik Williams

It is Black History Month and we have a very special episode to share with you. Allergy Partners’ physician, Dr. Aerik Williams, takes you along on his journey to becoming an allergist and discusses his recently published book. Whether you want to learn more about #racialissuesinhealthcare, are looking for an amazing biography to read, or want to get to know Dr. Williams a little better, this is the podcast for you.

We would like to not only recognize Dr. Aerik Williams, but to also celebrate him and his successes.

Dr. Williams has been with Allergy Partners since 2014. He joined Statesville, NC on 8/15/14 and went solo in Salisbury 1/1/2016. Since then, he has been repeatedly complimented by his staff and patients on his caring personality and professionalism.

In this very special podcast, Dr. Williams covers a wide range of topics from his memoirs, Aerik’s Anatomy, including:

• His personal experiences dealing with racism and stereotypes throughout his life

• Challenges in our healthcare system that are negatively impacting people of color

• His journey to achieve his lifelong goal to become a physician like his father

*Trigger warnings

Mental illness; racism and racial slurs; suicide; miscarriage.

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