Angioedema is the term for abnormal swelling of a particular area of the body due to fluid leaking from blood vessels just under the skin. Angioedema is most commonly seen with allergic reactions, but it is also seen with certain infections and illnesses.
Allergic angioedema may happen after bee stings, foods, medications, and “regular” causes of allergies such as pollens or animal dander. Angioedema can also occur repeatedly over a long period of time as part of a condition called “chronic urticaria”.
In addition, C-1 esterase inhibitor deficiency is a rare disorder of the clotting system that can lead to recurring swelling of both internal and external body parts. Most cases of C-1 esterase inhibitor deficiency are inherited and termed Hereditary Angioedema (HAE).